Table 2.
Vehicle |
ANG II |
|||
---|---|---|---|---|
C57BL/6J | Gal-3 KO | C57BL/6J | Gal-3 KO | |
HR, beats/min | 682 ± 16 | 640 ± 10 | 664 ± 11 | 660 ± 10 |
IVSTs, mm | 1.4 ± 0.1 | 1.4 ± 0.1 | 1.9 ± 0.1*** | 1.7 ± 0.1 |
LV PWTs, mm | 1.3 ± 0.05 | 1.4 ± 0.04 | 2.1 ± 0.1*** | 1.9 ± 0.1** |
LVDs, mm | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 |
LVAs, mm2 | 0.8 ± 0.1 | 0.9 ± 0.2 | 1.7 ± 0.1*** | 1.0 ± 0.2## |
IVSTd, mm | 0.9 ± 0.04 | 0.8 ± 0.02 | 1.2 ± 0.1*** | 1.1 ± 0.1* |
LV PWTd, mm | 1.0 ± 0.04 | 1.0 ± 0.04 | 1.5 ± 0.1*** | 1.4 ± 0.1** |
LVDd, mm | 2.4 ± 0.1 | 2.8 ± 0.1 | 2.2 ± 0.1# | 2.5 ± 0.2 |
LVAd, mm2 | 3.8 ± 0.1 | 4.6 ± 0.7 | 4.5 ± 0.3 | 4.2 ± 0.4 |
Values are means ± SE.
s, Systole; d, diastole; HR, heart rate; IVST, interventricular septum thickness; PWT, posterior wall thickness; LVA, LV area; LVD, LV dimension.
P < 0.05 vs. Gal-3 KO vehicle.
P < 0.01 vs. Gal-3 KO vehicle.
P < 0.001 vs. C57BL/6J vehicle.
P = 0.05 vs. Gal-3 KO ANG II.
P < 0.01 vs. C57BL/6J ANG II.