Fig. 3.
Evaluation of proteins or specific phosphoproteins in WT or DKO mice injected with CCl4 biweekly over a 4-wk period. A: we evaluated by immunoblot a number of molecules in lysates prepared from normal or fibrotic livers of WT or DKO mice. Contiguous lanes are represented in each subpanel. Albumin and actinin served as loading controls. SM, smooth muscle; HO-1, heme oxygenase-1; Glut. Syn., glutamine synthetase; AREG, amphiregulin; O.O., olive oil. B: all bars in graphs represent means + SE. Asterisks between bars represent a statistically significant comparison between WT and DKO groups. Asterisks above a line represent a statistically significant comparison between WT/DKO treated with O.O. compared with WT/DKO treated with CCl4. *P < 0.05.