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Effect of dietary K+ loading on the frequency distribution of BK channels in surface cells isolated from rat proximal (A) and distal (B) colon. The number of BK channels in cell-attached patches was decreased by K+ loading in proximal colon, while the opposite effect was seen in distal colon. Inset in B shows that a small number of patches in cells from distal colon of K+-loaded animals contained up to 6 BK channels.
