Table 1. Clinical findings in five cases with cutis tricolor syndrome.
| Main features | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
| Sex | Male | Female | Female | Male | Male |
| Age | 2 | 4 | 12 | 13 | 14 |
| Clinical manifestations | |||||
| Height | 25th | 50th | 95th | 75th | 50th |
| Weight | 50th | 50th | 97th | 97th | 50th |
| OFC | 25th | 50th | 98th | 25th | 50th |
| Cutis tricolor (pattern) | L, P | P | L, P | P | M |
| Face | + | − | − | + | − |
| Trunk | + | + | + | + | + |
| Upper limbs | − | + | + | − | − |
| Lower limbs | + | + | + | + | − |
| Coarse face | + | − | + | + | − |
| Facial asymmetry | + | − | + | + | − |
| Dolichocephalism | + | − | − | + | |
| Frontal bossing | + | − | + | + | − |
| Orbital bossing | + | − | + | + | − |
| Brushy eyebrows | + | + | + | + | + |
| Hypertelorism | + | − | + | + | − |
| Epicanthus | + | − | − | + | − |
| Deep nasal bridge | + | − | + | + | − |
| Large/bulbous nose | + | − | + | + | − |
| Large/anteverted nostrils | + | − | − | + | − |
| Low set ears | + | − | − | + | − |
| Posteriorly angulated ears | + | − | − | + | − |
| Wide philtrum | + | − | + | + | − |
| Prominent/thick lips | + | − | − | + | − |
| Prominent chin | + | + | + | + | − |
| Clinodactyly | + | + | + | − | − |
| Short neck | + | + | + | + | − |
| Pectus excavatum | + | + | + | + | + |
| Developmental milestoned | D | N | D | D | N |
| Hypotonia | + | − | + | + | − |
| Poor co-ordination | + | − | − | − | − |
| Language | D | N | D | D | N |
| Epilepsy | − | − | − | + | + |
| Onset | NA | NA | NA | 6y | 2y |
| Seizure type | NA | NA | NA | GTCS | GTCS |
| Outcome/age ceased | NA | NA | NA | 9y | 11y |
| Behavioural anomalies | + | − | − | + | + |
| Mental retardation | Mo | − | Mi | Mo | Mi |
| Other | − | − | Cataract | − | VSD |
OFC, occipitofrontal circumference; L, linear; P, patches; M, multiple maculae; +, present; −, absent; N, normal; D, delayed; NA, not applicable; y, years; GTCS, generalised tonic clonic seizures; Mi, mild; Mo, moderate; Se, severe; VSD, ventricular septal defect.