Fig. 7.

I–V relationships of native and SLC4A11-expressing oocytes in the presence of NH₄Cl. In native oocytes and SLC4A11-expressing oocytes, the current was recorded with a holding potential (V_h) of −40 mV, indicating the membrane conductance while perfused with Ringer's solution (control) and Ringer's solution containing 10 mM NH₄Cl at pH 7.4, 6.4, and 8.4. Experiments were performed in the nominal absence of CO₂/HCO₃⁻. Current-voltage relationships of NH₄Cl-induced membrane currents, as obtained from experiments in Fig. 6, C and D, is shown for both for both native (A) and SLC4A11-expressing (B) oocytes. Error bars represent means ± SE (n = 5–7).