Table 3.

HIV-positive and HIV-negative levels of cellular chemotaxis and inflammatory biomarkers in cerebrospinal fluid and serum. Significant differences are in bold typeface.

	CSF HIV+	CSF HIV−	Diff (95% CI)1	p	Serum HIV+	Serum HIV−	Diff (95% CI)1	p
Cytokines
TNFα	0.31 (0.51)	0.04 (0.24)	0.59 (0.2, 0.98)	0.004	0.94 (0.19)	0.79 (0.18)	0.82 (0.29, 1.34)	0.003
IFNy	0.29 (0.44)	0.07 (0.29)	0.53 (0.08, 0.97)	0.022	0.25 (0.46)	0.56 (0.47)	−0.67 (−1.22, −0.12)	0.019
IL1β	−0.10 (0.03)	−0.10 (0.00)	−0.28 (−0.6, 0.04)	0.088	−0.09(0.08)	−0.02(0.18)	−0.52 (−1.28, 0.24)	0.170
IL-2	0.02 (0.09)	0	0.27 (−0.05, 0.59)	0.100	0.08 (0.36)	0.08 (0.19)	0 (−0.41, 0.42)	0.990
IL-4	0.65 (0.00)	0.65 (0.00)	0 (0.0)	1.000	0.66 (0.15)	0.77 (0.39)	−0.44 (−1.25, 0.37)	0.270
IL-6	0.14 (0.32)	0.09 (0.27)	0.18 (−0.32, 0.68)	0.470	0.06(0.30)	0.08(0.26)	−0.05 (−0.55,0.46)	0.850
IL-7	0.28 (0.21)	0.17 (0.14)	0.59 (0.14, 1.03)	0.011	0.70 (0.35)	0.65 (0.28)	0.13 (−0.36, 0.62)	0.600
IL-10	0.26 (0.43)	0.04 (0.0)	0.60 (0.28, 0.93)	0.0005	0.31 (0.42)	0.30 (0.40)	0.02 (−0.52, 0.55)	0.950
Chemokines
IP-10	3.29 (0.83)	2.98 (0.20)	0.43 (0.08, 0.77)	0.015	2.98 (0.31)	2.57(0.20)	1.42 (0.98, 1.87)	<0.0001
MCP-1	3.15 (0.20)	3.05 (0.12)	0.57 (0.14, 1.0)	0.010	2.73(0.22)	2.63(0.22)	0.45 (−0.1, 1)	0.100
MIP-1α	1.09 (0.14)	1.01 (0.06)	0.65 (0.26, 1.04)	0.001	0.65(0.32)	0.64(0.29)	0.03 (−0.49, 0.55)	0.900
MIP-1β	1.06 (0.29)	0.95 (0.30)	0.38 (−0.18, 0.93)	0.170	1.71(0.28)	1.72(0.19)	−0.04 (−0.49, 0.42)	0.880
RANTES	0.60 (0.64)	0.37 (0.57)	0.37 (−0.15, 0.89)	0.150	4.49(0.26)	4.75(0.20)	−1.04 (−1.51, −0.56)	<0.0001

Values are log₁₀ transformed pg/mL, presented as mean (SD).

¹Groups differences presented as Cohen´s d effect sizes and 95% confidence intervals.