Table 1.

US Preventive Services Task Force–Assigned Recommendation Grade and Practice Suggestion by Cancer Screening Decision

Screening Decision	Recommendation Grade	Practice Suggestion
• Cervical cancer screening in women aged 21–65 years • Colorectal cancer screening in adults aged 50–75 years	A High certainty net benefit is substantial.	Offer or provide service
• Lung cancer screening in adults aged 55–80 years, who smoke or recently quit • Screening mammography in women aged 50–74 years	B High certainty net benefit is moderate or moderate certainty net benefit is moderate to substantial.	Offer or provide service
• Screening mammography in women before the age of 50 • Colorectal cancer screening in adults aged 75–85 years	C At least moderate certainty net benefit is small.	Offer/provide for selected patients depending on individual circumstances
• Cervical cancer screening in previously screened, average risk women >65 years • PSA in average risk men • Colorectal cancer screening in adults >85 years	D Moderate or high certainty that the service has no benefit or that the risks outweigh the benefits.	Discourage use
• Mammography in women >=75 years • Skin exam for cutaneous melanoma, basal cell cancer, or squamous cell skin cancer	I Insufficient evidence to assess benefit/risk balance. Evidence lacking, poor quality, or conflicting.	If offered, patients should understand uncertainty regarding balance of benefits/risks