Table 2.

Pregnancy outcomes in the daclizumab clinical study program

Pregnancies by outcomea	Became pregnant while receiving daclizumab or ≤6 months after the final dose	Stopped daclizumab treatment >6 months before becoming pregnant	Daclizumab dose status unknown at the time of becoming pregnant
Total number of pregnancies	38	6	1
Total number of women who became pregnantb	36c	5d	1
Live birth	20	3	0
Spontaneous abortion/miscarriage	4	2	0
Elective termination	8	1	0
Ectopic pregnancy	2	0	0
Lost to follow-up	2	0	0
Outcome pending	2	0	1

^aBased on pregnancy reports from the daclizumab drug development program as of March 9, 2015

^bFour women became pregnant more than once; two of these women became pregnant while receiving daclizumab or ≤6 months of receiving the final dose and then again >6 months after their final dose of daclizumab and are therefore counted in both columns

^cOf the 36 women who became pregnant while receiving daclizumab or ≤6 months of receiving the final dose, 34 had one pregnancy (total pregnancies, n = 34) and two had two pregnancies in this category (total pregnancies, n = 4)

^dIn the five women who became pregnant >6 months after their final dose of daclizumab, four had one pregnancy each (total pregnancies, n = 4) and one had multiple (n = 2) pregnancies in this category