Table 4. Univariate and multivariate Cox regression models by ATM, ATR, Chk1 and Chk2 genotypes.

Univariate Cox regression models
	OS				PFS
ATMrs664677
(T/T vs C/T, C/C)	0.94	0.7	1.27	0.684	1	0.75	1.35	0.974
ATMrs664143
(G/G vs A/G, A/A)	0.94	0.7	1.27	0.697	1	0.75	1.34	0.991
ATRrs2229032
(C/C vs C/T, T/T)	0.92	0.66	1.29	0.634	0.83	0.6	1.15	0.266
ATRrs2227928
(G/G vs A/G, A/A)	1.02	0.75	1.37	0.916	0.97	0.73	1.31	0.857
Chk1 rs521102 (A/A)	reference				reference
(A/G)	1.09	0.76	1.56	0.635	1.12	0.79	1.6	0.511
(G/G)	1.31	0.89	1.93	0.164	1.25	0.86	1.82	0.246
Chk2 rs2267130 (C/C)	reference				reference
(C/T)	1.05	0.74	1.48	0.804	0.95	0.68	1.34	0.786
(T/T)	0.9	0.6	1.33	0.585	0.8	0.54	1.17	0.251
Multivariate Cox regression models
ATMrs664677
(T/T vs C/T, C/C)	0.84	0.62	1.13	0.245	0.91	0.68	1.22	0.531
ATMrs664143
(G/G vs A/G, A/A)	0.87	0.65	1.18	0.379	0.94	0.7	1.26	0.682
ATRrs2229032
(C/C vs C/T, T/T)	1.03	0.74	1.45	0.852	0.91	0.66	1.27	0.591
ATR rs2227928
(G/G vs A/G, A/A)	0.93	0.69	1.26	0.639	0.87	0.64	1.17	0.341
Chk1 rs521102 (A/A)	reference				reference
(A/G)	1.06	0.74	1.52	0.745	1.09	0.77	1.55	0.627
(G/G)	1.48	1	2.18	0.047	1.37	0.94	2	0.103
Chk2 rs2267130 (C/C)	reference				reference
(C/T)	1.08	0.76	1.54	0.656	0.99	0.7	1.4	0.946
(T/T)	1.01	0.68	1.5	0.971	0.87	0.59	1.28	0.482

HR: Hazard Ratio; CI: Confidential Interval.