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. 2016 Nov 16;1(5):952–962. doi: 10.1021/acsomega.6b00126

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Copyright © 2016 American Chemical Society

This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License, which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.

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Viability of the PC3 cells in monolayer cultures. (A) Cell viability with media only (control, cyan bar), nontargeted polymersomes (pink bar), targeted polymersomes (green bar), nontargeted polymersomes encapsulating docetaxel (red bar), free docetaxel (orange bar), and targeted polymersomes encapsulating docetaxel (purple bar). (B) Cell viability with media only (control, cyan bar), nontargeted polymersomes (pink bar), targeted polymersomes (green bar), nontargeted polymersomes encapsulating mocetinostat (red bar), free mocetinostat (orange bar), and targeted polymersomes encapsulating mocetinostat (purple bar). (C) Cell viability with media only (control, cyan bar), nontargeted polymersomes (pink bar), targeted polymersomes (green bar), nontargeted polymersomes encapsulating docetaxel/mocetinostat (red bar), free docetaxel and mocetinostat (orange bar), and the combination of targeted polymersomes encapsulating docetaxel/mocetinostat (purple bar). Error bars denote the mean ± SEM.