Table 1. Estimates of pharmacodynamic parameters of enrofloxacin against Pasteurella multocida isolates with different MIC.

Isolate source	MIC(μg/mL)	Parameter	Estimate	CV (%)	2.5% CI of the estimate	97.5% CI of the estimate
Bovine lung	0.01	Emax	1.64	8.47	1.34	1.93
		EC50, μg/mL	0.11	11.49	0.08	0.13
		E0, log(CFU/mL) x hour−1	0.32	8.86	0.26	0.38
		H	0.97	11.97	0.73	1.22
Bovine nasal swab	1.50	Emax	0.81	9.07	0.65	0.96
		EC50, μg/mL	2.13	13.13	1.53	2.72
		E0, log(CFU/mL) x hour−1	0.31	10.40	0.24	0.38
		H	3.05	14.22	2.13	3.97
Bovine nasal swab	2.00	Emax	0.69	4.37	0.63	0.75
		EC50, μg/mL	1.60	3.38	1.49	1.72
		E0, log(CFU/mL) x hour−1	0.29	3.11	0.27	0.30
		H	4.37	17.28	2.77	5.97