Table 1.
Subject characteristics at baseline
| LIS subjects | OIR subjects | P | Adjusted P * | |
|---|---|---|---|---|
| Age (years) | 23.22 ± 0.22 | 28.56 ± 1.40 | 0.002 | |
| BMI (kg/m2) | 22.01 ± 0.18 | 30.15 ± 0.75 | <0.001 | <0.001 |
| Waist Circumference (cm) | 79.94 ± 0.54 | 100.78 ± 0.98 | <0.001 | <0.001 |
| Fasting Blood Glucose (mmol/l) | 4.33 ± 0.05 | 4.68 ± 0.12 | 0.026 | 0.459 |
| Fasting Serum Insulin (mU/l) | 4.31 ± 0.52 | 21.04 ± 2.27 | <0.001 | <0.001 |
| Fasting Total Cholesterol (mmol/l) | 5.09 ± 0.27 | 5.28 ± 0.40 | 0.697 | 0.791 |
| Fasting Triglyceride (mmol/l) | 0.62 ± 0.07 | 1.98 ± 0.24 | <0.001 | 0.007 |
| Fasting LDL-Cholesterol (mmol/l) | 3.09 ± 0.29 | 3.20 ± 0.35 | 0.823 | 0.730 |
| Fasting HDL-Cholesterol (mmol/l) | 1.71 ± 0.08 | 1.19 ± 0.06 | 0.001 | 0.005 |
| Fasting NEFA (mmol/l)a | 0.41 ± 0.04 | 0.49 ± 0.03 | 0.037 | 0.392 |
| Systolic Blood Pressure (mmHg) | 110.78 ± 4.07 | 119.78 ± 2.61 | 0.084 | 0.705 |
| Diastolic Blood Pressure (mmHg) | 60.56 ± 3.00 | 71.44 ± 3.18 | 0.024 | 0.468 |
| HOMA-IR | 0.83 ± 0.10 | 4.34 ± 0.41 | <0.001 | <0.001 |
Data presented as mean ± standard errors of mean. HOMA-IR Homeostatic model assessment-insulin resistance, NEFA Nonesterified fatty acids, LIS Lean insulin sensitive, OIR Obese insulin resistant, *P-value adjusted for age. aAnalysis was done on log transformed data-sets