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. 2016 Dec 1;5:111. doi: 10.1186/s40249-016-0209-7

Table 4.

Radiological and serological results of TSOL+ individuals of the matched and initially recruited population

P 1 P 2 P 3 P 4 P 5 P 6 P 7 P 8 P 9 P 10
Matched study group yes yes yes yes yes yes yes yes no no
 Age 50 46 45 60 46 28 27 51 38 14
 Gender f m m m m f f m m m
First clinical examination
 HIV parameters
  HIV status + + + + - - - - - -
  HIV stage I I I III - - - - - -
  HAART drugs ZDV/3TC/EFZ ZDV/3TC/EFZ ZDV/3TC/EFZ ZDV/3TC/EFZ - - - - - -
 HAART treatment since (years) <1 3 3 4 n.a. n.a. n.a. n.a. n.a. n.a.
 NCC symptoms/signs - - - headaches - severe headaches - - epi epi, enca
 CT diagnosis
  Calcified cysts + - + + o o o o + -
  Viable cysts - - - - o o o o - +
Other NCC relevant findings - - - - o o o o - hydrocephalus
 Laboratory diagnosis
  CD4+ counts 554 433 276 170 n.a. n.a. n.a. n.a. n.a. n.a.
  CC- Ab + + + + + + + + + +
  CC-Ag - - - + - - - - - +
  Taeniosis-Ab + - - - - - + + + +
Second clinical examination
 NCC symptoms/signs x x - - - severe headaches - x d epi, enca
 CT diagnosis x
  Calcified cysts x x + + + - + x d +
  Viable cysts x x - - - - - x d +
  Other NCC relevant findings x x - - - hydrocephalusb - x d hydrocephalus
 Laboratory findings
  CD4+ counts 521 400 368 184 n.a. n.a. n.a. n.a. d n.a.
  CC-Ab + + - - + x x x d x
  CC-Ag - - - + - x x x d x
  Taeniosis-Ab + - - - - x x x d x
  Taeniosis-copro-Ag - - - - - - - x d x

P patient number, m male, f female, HIV human immunodeficiency virus, HAART highly active antiretroviral therapy, ZDV zidovudine, 3TC lamivudine, EFZ efavirenz, NCC neurocysticercosis, epi epilepsy, enc encephalopathy, CT computed tomography, CD4 + CD4+ T-lymphocyte cell counts, n.a. not applicable, because in the group of HIV– these parameters were not tested and no HAART was taken, CC cysticercosis, Ab antibodies, Ag antigen, + positive, − negative, o was not taken at once due to ethical concerns of performing a CT scan in healthy individuals, but was offered when the positive test serology was confirmed, x patient refused or was not found, d patient died before 2nd examination with unclear diagnosis (strong headaches and abdominal pain reported before death)

aPatient was unconscious with signs of brainstem involvement and generalized increased muscle tone leading to flexion contractures of all four limbs, most likely in the context of increased intracranial pressure

bMass in 4th ventricle causing obstructive hydrocephalus