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. 2016 Dec 1;39:2. doi: 10.1186/s41021-016-0051-y

Table 1.

Expected functions of cellular proteins related to mutations by GO directly produced in DNA

Protein Role
Specialized DNA pol
pol η error-free bypass
pol ζ error-free bypass
pol κ error-prone bypass
pol λ error-free bypass, suppression of untargeted mutations
DNA glycosylase
OGG1 suppression of G→T mutation by GO removal
MUTYH suppression of G→T mutation by A removal
NTH1 suppression of G→T mutation
NEIL1 suppression of G→T mutation
WRN suppression of untargeted mutations