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. 2016 Dec 1;6:38108. doi: 10.1038/srep38108

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Real-time PCR analysis for Nav1.6 expression in the hippocampus in PTZ-kindled animals and the control groups. Each column represents mean ± SEM of five animals in each group. *P < 0.05, **P < 0.01, significantly different from the control animals. (B–E) A small amount of Nav1.6-ir is observed in the stratum pyramidale in the hippocampus in PTZ-kindled animals and the controls. Nav1.6-ir (red) is not co-localized with GFAP-ir positive cells (green) both in the controls and PTZ-kindled rats (B,C). Nav1.6-ir (red) is located in NeuN-ir positive cells (green) both in the controls and PTZ-kindled rats (D,E).