Table 3. Hematological parameters and red cell indices at PND 360.
Ctrl (n = 10) | ETU (0.1 mg/kg/day) (n = 4) | CPF (0.1 mg/kg/day) (n = 4) | ETU + CPF (0.1 mg/kg/day) (n = 10) | |
---|---|---|---|---|
Hct (%) | 47.2 ± 1.08 | 42.6 ± 2.2* | 41.0 ± 2.6* | 40.3 ± 1.6* |
Hb (g/dl) | 15.6 ± 0.7 | 13.8 ± 1.2* | 13.6 ± 0.9* | 13.2 ± 0.4* |
MCV (fl) | 53.4 ± 1.0 | 52.7 ± 1.1 | 52.3 ± 0.5 | 52.7 ± 0.7 |
MCH (g/dl) | 16.7 ± 1.5 | 15.0 ± 0.7 | 14.8 ± 2.6* | 14.1 ± 0.5* |
Retics (103 cells/μL) | 194 ± 48 | 135 ± 24 | 113 ± 15 | 73.9 ± 19* |
WBC (cells/μL) | 1330 ± 324 | 450 ± 278* | 780 ± 451* | 862 ± 181* |
N (cells/μL) | 378 ± 115 | 134 ± 69 | 273 ± 108 | 157 ± 27 |
L (cells/μL) | 540 ± 279 | 240 ± 131 | 321 ± 158 | 433 ± 95 |
M (cells/μL) | 16 ± 7.8 | 2.52 ± 0.9* | 14.8 ± 9.4 | 4.2 ± 0.1* |
PLTs (103 cells/μL) | 847 ± 12 | 743 ± 5 | 731 ± 11 | 169 ± 9.0* |
Hct: hematocrit; Hb: hemoglobin; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; Retics: reticulocytes; MCVr: mean corpuscular volume reticulocytes; WBC: white blood cells; N: neutrophil; L: lymphocyte; M: monocyte; PLTs: platelets. Data are reported as means ± SD. In bold the ones reaching statistical significance.