Table 3.
Adjusted Median Regressions of Cognitive Function Predicting 21-Day Medication Adherence (% of Days Adherent)
| Cognitive Domainsa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Attention | Executive Attention | Memory | |||||||
|
| |||||||||
| Variables | β (95%CI) | SE | p | β (95%CI) | SE | p | β (95%CI) | SE | p |
| Demographic/Medical | |||||||||
| Age | 0.27 (−0.06, 0.59) | 0.17 | .110 | 0.35 (0.09, 0.60) | 0.13 | .009* | 0.17 (−0.16, 0.50) | 0.17 | .319 |
| Race-ethnicity | −5.05 (−13.20, 3.10) | 4.14 | .224 | −4.57 (−10.96, 1.82) | 3.24 | .160 | −6.80 (−15.33, 1.74) | 4.33 | .118 |
| SES | 0.41 (−0.40, 1.23) | 0.41 | .320 | 0.46 (−0.17, 1.10) | 0.32 | .152 | 0.57 (−0.27, 1.41) | 0.43 | .182 |
| Self-reported NYHA | |||||||||
| Class II | −6.50 (−17.69, 4.69) | 5.69 | .254 | −5.36 (−14.14, 3.41) | 4.46 | .230 | −9.21 (−20.81, 2.39) | 5.89 | .119 |
| Class III | −6.18 (−16.67, 4.32) | 6.33 | .248 | −5.52 (−13.70, 2.66) | 4.15 | .185 | −7.95 (−18.78, 2.89) | 5.50 | .150 |
| Class IV | −23.65 (−40.48, −6.82) | 8.55 | .006* | −23.64 (−36.70, −10.57) | 6.63 | .001* | −18.92 (−36.1, −1.75) | 8.72 | .031* |
| Psychosocial | |||||||||
| Depression (PHQ-9) | −0.55 (−1.25, 0.15) | 0.36 | .124 | −0.48 (−1.03, 0.08) | 0.28 | .090 | −0.62 (−1.34, 0.08) | 0.36 | .081 |
| Social Support (MSPSS) | 0.19 (−0.03, 0.41) | 0.11 | .098 | 0.16 (−0.02, 0.34) | 0.09 | .087 | 0.21 (−0.02, 0.44) | 0.12 | .071 |
| Cognitive Domains | |||||||||
| Attention | 0.34 (−0.12, 0.57) | 0.22 | .131 | -- | -- | -- | -- | -- | -- |
| Executive Function | -- | -- | -- | 0.24 (0.02, 0.51) | 0.14 | .075 | -- | -- | -- |
| Memory | -- | -- | -- | -- | -- | -- | 0.51 (0.14, 0.89) | 0.19 | .008* |
Note. SES = socioeconomic status. NYHA = New York Heart Association. PHQ-9 = Patient Health Questionnaire. MSPSS = Multidimensional Scale of Perceived Social Support.
a
Each cognitive domain was examined in a separate model.
*
Significant at p < .05