Table 3.
Kendall’s correlation analysis of methylation status of the oxytocin receptor gene in relation to demographic and clinical variables in patients with obsessive–compulsive disorder (n = 42)
| OXTR gene | CpG island unit | Age | Sex | Level of education | BDI | BAI | Tics | Y-BOCS |
|---|---|---|---|---|---|---|---|---|
| OXTR1 | 1 | τ = 0.046 (0.679) | τ = 0.001 (0.999) | τ = −0.089 (0.434) | τ = −0.272 (0.013) | τ = −0.115 (0.296) | τ = −0.082 (0.534) | τ = 0.013 (0.913) |
| OXTR1 | 2 | τ = 0.034 (0.760) | τ = 0.157 (0.227) | τ = −0.029 (0.799) | τ = −0.141 (0.199) | τ = −0.055 (0.617) | τ = 0.082 (0.534) | τ = 0.058 (0.601) |
| OXTR1 | 3 | τ = 0.086 (0.434) | τ = 0.168 (0.198) | τ = 0.059 (0.604) | τ = −0.322 (0.003) | τ = −0.122 (0.267) | τ = 0.087 (0.509) | τ = −0.118 (0.286) |
| OXTR1 | 4 | τ = 0.150 (0.171) | τ = 0.011 (0.937) | τ = −0.009 (0.938) | τ = −0.336 (0.002) | τ = −0.167 (0.128) | τ = −0.077 (0.560) | τ = −0.029 (0.793) |
| OXTR2 | 1 | τ = −0.023 (0.839) | τ = −0.119 (0.371) | τ = −0.074 (0.522) | τ = −0.284 (0.010) | τ = −0.165 (0.137) | τ = −0.156 (0.239) | τ = −0.033 (0.769) |
| OXTR2 | 2 | τ = −0.023 (0.839) | τ = −0.129 (0.329) | τ = −0.053 (0.647) | τ = −0.244 (0.028) | τ = −0.153 (0.169) | τ = −0.135 (0.309) | τ = −0.041 (0.718) |
| OXTR2 | 3 | τ = 0.026 (0.821) | τ = −0.039 (0.772) | τ = −0.069 (0.552) | τ = −0.264 (0.017) | τ = −0.138 (0.215) | τ = −0.098 (0.461) | τ = −0.043 (0.701) |
| OXTR2 | 4 | τ = −0.021 (0.857) | τ = −0.068 (0.611) | τ = −0.050 (0.663) | τ = −0.234 (0.035) | τ = −0.130 (0.241) | τ = −0.104 (0.437) | τ = −0.046 (0.684) |
| OXTR2 | 5 | τ = −0.021 (0.857) | τ = −0.071 (0.591) | τ = −0.066 (0.567) | τ = −0.259 (0.019) | τ = −0.135 (0.223) | τ = −0.072 (0.590) | τ = −0.048 (0.668) |
OXTR oxytocin receptor, CpG cytosine-phosphate-guanine, BDI Beck Depression Scale Inventory, BAI Beck Anxiety Scale Inventory, Y-BOCS Yale-Brown Obsessive–Compulsive Scale, τ Kendall’s tau rank correlation coefficient
Values are presented as τ (p)