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. 2016 Dec 1;13:64. doi: 10.1186/s12989-016-0177-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Cytokine expression profile in the ApoE^−/− hippocampus after acute (1-day) exposure to atmospheres. After 1-day of exposure to atmospheres, cytokine mRNA expression was assessed in the hippocampus of the ApoE^−/− mouse brain for the following: (a) Ccl5, (b) Cxcl1, (c) IL-1β, (d) IL-6, (e) Tgf-β, and (f) Tnf-α. None of the exposures significantly altered mRNA expression of (a) Ccl5 or (b) Cxcl1. Exposure to UFP and UFP + G significantly altered mRNA expression of (c) IL-1β, (d) IL-6, (e) Tgf-β, and (f) Tnf-α, with exposures having the greatest impact on (f) Tnf-α expression. n = 7–8 per group, *p < .05; **p < .01; ***p < .001