Fig. 2.

Metabolic correlations associated with mitochondrial respiratory parameters.

Data represented are from perinatally HIV-infected youth (N = 66). (a) Relationship between basal respiration and homeostatic model assessment of insulin resistance with and without IR. An inverse relationship exists between basal respiration and insulin-resistant status as determined by homeostatic model assessment of insulin resistance (P value = 0.0091, rho = −0.32). (b) Relationship between nonmitochondrial respiration and fasting glucose. A positive correlation exists between fasting glucose and nonmitochondrial respiration (P value = 0.02, rho = 0.29).