Fig. 2.

Mice given access to alcohol–quinine in the initial 24-h session showed significantly reduced intake and preference during that session. Alcohol intake (A) and preference (B) in different experimental groups during the initial 24-h session. Blue columns: Alc-only mice, n = 40; red columns: Alc-then-AlcQ mice, n = 29; red-brown with white-hatched columns: AlcQ-only mice, n = 12; purple columns: AlcBrief-then-AlcQ mice, n = 15; green columns: H2O-then-AlcQ mice, n = 12. Data are shown as mean ± SEM. **p < 0.01 versus all other groups; #p < 0.01 between indicated group and both Alc-only and Alc-then-AlcQ mice. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)