. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Respir Med. 2016 Oct 19;121:13–20. doi: 10.1016/j.rmed.2016.10.010

Table 3.

Association of birth weight, gestational age and gestational maternal smoking with lung function: repeated-measurement analysis

Predictor	FEV₁ (mL)		FVC (mL)		FEV₁/FVC (%)		FEF_25-75 (mL)
Predictor	Est. ± SE	P-value	Est. ± SE	P-value	Est. ± SE	P-value	Est. ± SE	P-value
(n=1121)
Birth weight (kg)^†	42.6 ± 17.4	0.0145	35.0 ± 18.1	0.0536	0.1 ± 0.4	0.8747	95.5 ± 41.2	0.0207
Gestational age (weeks)^§	3.1 ± 5.2	0.5515	−3.3 ± 5.5	0.5484	0.2 ± 0.1	0.0885	18.7 ± 12.1	0.1242
Maternal smoking during pregnancy: Yes^‡	0.5 ± 17.0	0.9781	−0.1 ± 18.0	0.9964	−0.3 ± 0.4	0.4694	−48.0 ± 39.9	0.2284

^†

Models adjusted for maternal smoking during pregnancy, sex, height, age, gestational age, maternal history of asthma, admission to Neonatal Intensive Care Unit, smoking at 18 years of age, height*sex

^‡

Models adjusted for sex, height, age, gestational age, maternal history of asthma, admission to Neonatal Intensive Care Unit, smoking at 18 years of age, height*sex

^§

Models adjusted for sex, height, age, maternal smoking during pregnancy, maternal history of asthma, admission to Neonatal Intensive Care Unit, smoking at 18 years of age, height*sex.