Skip to main content
. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Cell Rep. 2016 Nov 15;17(8):1915–1922. doi: 10.1016/j.celrep.2016.10.065

Figure 1.

Figure 1

Ndc80c. (A) Schematic of Ndc80c. Upper diagram: Ndc80c was shortened by joining the globular ends of each heterodimer (Ndc80:Nuf2 or Spc24:Spc25) to the beginning of a heptad in the CC region, as illustrated by the dashed line. Lower diagram: The shortened Ndc80c retains the junction (J). Color code, used in all figures: Ndc80, red, Nuf2, orange, Spc24, green, Spc25, blue. (B) Polypeptide chains of Ndc80cdwarf (left) and Ndc80ce-dwarf (right). Numbers indicate boundaries determined from the crystal structures. The two additional heptads in Scp24e-dwarf and Spc25e-dwarf are in blue and yellow, respectively. Polypeptide chains of Ndc80ce-dwarf and Ndc80dwarf are otherwise identical. CH: calponin homology domains; RWD: RWD domains; CC: coiled-coil regions, including residues in junction.