Table 2. Isothermal titration calorimetry of ComR S. suis variants and XIP.
ComR | XIP | N | (+/-) | Kd (μM) | (+/-) | ΔH (cal mol-1) | (+/-) | ΔS (cal K-1 mol -1) |
---|---|---|---|---|---|---|---|---|
wild-type | suis C7 | 0.96 | 0.015 | 0.862 | 0.121 | -13550 | 319 | -17.76 |
K260A | suis C7 | - | - | - | - | - | - | - |
N220A | suis C7 | 1.092 | 0.139 | 13.7 | 3 | -7280 | 1228 | -2.186 |
wild-type | mutans C7 | 1.035 | 0.05 | 5.88 | 0.968 | -6013 | 408 | 3.75 |
N220A | mutans C7 | 0.95 | 0.069 | 6.06 | 1.29 | -4259 | 413 | 9.58 |