Table 3. Independent predictors of pregnancy outcomes.
Predictor | Univariate | Adjusted1 | ||||
---|---|---|---|---|---|---|
Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | p-value | |
Diagnosis | <.001 | <.001 | ||||
Normal chromosomes | 1 | 1 | ||||
Aneuploidy | 304.50 | 250.98–369.44 | <.001 | 437.40 | 348.19–549.46 | <.001 |
Other anomaly | 97.00 | 72.43–129.91 | <.001 | 95.94 | 69.21–133.01 | <.001 |
Year | <.001 | .972 | ||||
2000–2003 | 1 | 1 | ||||
2004–2007 | 1.27 | 1.12–1.44 | <.001 | 0.98 | 0.79–1.22 | .874 |
2008–2011 | 1.37 | 1.20–1.55 | <.001 | 0.97 | 0.78–1.22 | .815 |
Age | ||||||
<35 | 1 | 1 | ||||
≥35 | 0.59 | 0.53–0.65 | <.001 | 0.35 | 0.28–0.42 | <.001 |
SIMD | .001 | .221 | ||||
1 (least affluent) | 1 | 1 | ||||
2 | 0.98 | 0.81–1.18 | .822 | 1.24 | 0.91–1.70 | .174 |
3 | 0.73 | 0.60–0.88 | .001 | 0.88 | 0.64–1.21 | .434 |
4 | 0.77 | 0.64–0.92 | .003 | 0.99 | 0.73–1.34 | .934 |
5 (most affluent) | 0.84 | 0.71–0.99 | .040 | 1.10 | 0.82–1.47 | .538 |
Parity | .037 | |||||
0 | 1 | 1 | ||||
1 | 0.81 | 0.72–0.92 | .001 | 0.86 | 0.70–1.06 | .159 |
≥2 | 0.79 | 0.69–0.90 | .001 | 0.73 | 0.58–0.93 | .011 |
CI confidence interval; SIMD Scottish Index of Multiple Deprivation.
1Adjusted for diagnosis, year of testing, maternal age, SIMD quintiles, parity