Table 7. Mutation type of rdxA related to metronidazole resistance.
| No | Strain | MIC | Sites of Mutation | Type of mutation |
|---|---|---|---|---|
| 1 | Jayapura16 | 32 | R16C, A183V | Missense mutation |
| 2 | Kupang23 | >256 | E15Q, R16H, E32D, E34stop | Premature stop codon |
| 3 | Kupang 30 | 96 | R90K, P106S, V111A | Missense mutation |
| 4 | Kupang 41 | 64 | Q6H, R16C, R90K, E175Q, N178D, A183V | Missense mutation |
| 5 | Kupang 5 | 12 | A68V | Missense mutation |
| 6 | Kupang 73 | 48 | K64N, H97T, P106S, H127Y, Q197stop | Premature stop codon |
| 7 | Malang1 | 48 | 16frameshift | Frameshift mutation |
| 8 | Manado26 | 64 | None | Non-specific mutation |
| 9 | Manado 31 | 48 | 65frameshift | Frameshift mutation |
| 10 | Medan3 | 16 | 65frameshift | Frameshift mutation |
| 11 | Medan10 | >256 | H97Y, P106T, G122S | Missense mutation |
| 12 | Medan15 | 64 | P51S, A68T, E175Q, R176H | Missense mutation |
| 13 | Medan17 | 128 | R16C, A68T, G122S, C159Y | Missense mutation |
| 14 | Medan18 | 64 | R90K, 195frameshift | Frameshift mutation |
| 15 | Medan19 | 128 | Q6H, R16C, R90K, H97T, A118S, E175Q, A183V, V204I | Missense mutation |
| 16 | Medan20 | 64 | K64N, H97Y, P106T, G122S, 137frameshift | Frameshift mutation |
| 17 | Medan22 | 32 | R16H, K64N, H97Y, P106M, G122S, E175Q | Missense mutation |
| 18 | Medan23 | 24 | V55M, K64N, G122S, E175Q, A183V, | Missense mutation |
| 19 | Medan25 | 64 | M1V, R16C, K64N, A80T, H97Y, P106T, G122S, E175Q | Missense mutation |
| 20 | Medan27 | >256 | 4frameshift | Frameshift mutation |
| 21 | Medan28 | 48 | P51S, K64N, M102stop, P106L, 173frameshift | Frameshift mutation |
| 22 | Medan30 | 96 | None | Non-specific mutation |
| 23 | Medan31 | 96 | K64N, H97I, P106T, G122S, E175stop | Premature stop codon |
| 24 | Medan32 | 32 | R10I, A68V, G145R | Missense mutation |
| 25 | Medan33 | 96 | R10S, H97Y, P106T, G122S, 169frameshift | Frameshift mutation |
| 26 | Makassar52 | 64 | None | Non-specific mutation |
| 27 | Makassar55 | 96 | Q6H, R16H, M56I, R90K, H97Y, P166S, | Missense mutation |
| 28 | Pontianak20 | >256 | G163D, E173stop | Premature stop codon |
| 29 | Surabaya68 | 24 | R16H, P106T, V204I | Missense mutation |
| 30 | Surabaya69 | 32 | None | Non-specific mutation |
| 31 | Surabaya79 | 128 | Q6H, R16C, M56I, A80T, R90K, H97Y | Missense mutation |
| 32 | Surabaya137 | >256 | 23frameshift | Frameshift mutation |
| 33 | Surabaya283 | 32 | Q146stop | Premature stop codon |
| 34 | Surabaya304 | 64 | I182V | Missense mutation |
R16C means Cysteine replaced Arginine amino acid in the position 16; E34stop means stop codon replaced Glutamate amino acid in the position 34; 16frameshift means frameshift mutation in the position 16.