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Levels of biomarker analytes were compared at P12 in ASO-SMA mice (n = 12), in SMA mice (n = 13), ASO-Het (n = 10), and Het mice (n = 5). ASO-Het mice were considered controls for statistical comparison using One-way ANOVA and Dunnett's multiple comparisons test (GraphPad Prism, La Jolla CA). Statistical differences between cohorts and controls are shown as * <0.05, ** <0.01, *** <0.001.
