Table 3. Biomarkers in SMA Mice, SMN-restored Mice, and Human SMA.

Biomarker	Change in SMA mice	Normalized with SMN	Correlation with MHFMS(Kobayashi et al. 2013)	Change in SMA (<6 months) (Kolb et al. 2016)
Osteopontin	Increased	Yes	Direct	No change
DPPIV	Increased	Yes	Direct	Increased
Tetranectin	Increased	Yes	Direct	Increased
Fetuin A	Decreased	Yes	Inverse	No change
Vitronectin	Decreased	Yes	Inverse	Not performed