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. 2016 Oct 28;64(6):1934–1950. doi: 10.1002/hep.28819

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© 2016 The Authors. Hepatology published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Phylogenetic analysis of HEV complete genome sequences. A neighbor‐joining tree was produced using a Poisson model of AA distances between 36 concatenated ORF1 and ORF2 regions (but not including the ORF1 hypervariable region) from human‐derived HEV genotype 3 isolates (open circles), rabbit‐derived genotype 3 isolates (open triangles), and reference sequences of other genotypes (open squares). Sequence HQ389543 (subtype 3a) that was used to generate the peptide set is shown with a filled circle. Branches supported by >70% of bootstrap replicates are indicated.