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. 2016 Oct 22;140(2):400–410. doi: 10.1002/ijc.30461

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© 2016 The Authors International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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(a) Representative data of chromosome positions in interphase nuclei of lymphocytes, MGUS and MM after conventional 3D epifluorescence microscopy. Visualization of the 2D image and 3D reconstruction of specific CTs after 3D‐FISH using human whole chromosome painting probes on lymphocytes (left), MGUS cells (middle) and MM cells (right panel). (A) chromosome 4 (red) and 14 (green); (B) chromosome 11 (red) and 14 (green); (C) chromosome 14 (green) and 16 (red); (D) chromosome 9 (red) and 22 (green); and (E) chromosome 18 (red) and 19 (green). DNA counterstain is shown in blue (scale bar = 7 μm).