Table 2.
Mean CTs volume of each chromosome in lymphocyte, MGUS and MM nuclei
| Mean absolute CTs volumes | Normalized CTs volumes | |||||
|---|---|---|---|---|---|---|
| Chromosome | Lymphocyte | MGUS | MM | Lymphocyte | MGUS | MM |
| 4 | 6.01 ± 3.32 |
7.26 ± 5.05 (0.009) |
9.23 ± 5.89 (<0.001) |
2.19 ± 1.09 |
1.64 ± 0.96 (<0.001) |
1.96 ± 1.08 (<0.001) |
| 9 | 4.70 ± 2.55 |
5.41 ± 4.92 (<0.001) |
6.25 ± 4.05 (<0.001) |
1.69 ± 0.77 | 1.07 ± 0.74 (<0.001) |
1.34 ± 0.74 (<0.001) |
| 11 | 5.20 ± 2.62 |
6.92 ± 5.01 (<0.001) |
5.95 ± 4.66 (0.048) |
1.85 ± 0.89 |
1.37 ± 0.92 (<0.001) |
1.12 ± 0.70 (<0.001) |
| 14 | 5.08 ± 2.68 |
5.87 ± 3.90 (<0.001) |
6.46 ± 4.73 (<0.001) |
1.82 ± 0.92 |
1.24 ± 0.81 (<0.001) |
1.29 ± 0.77 (<0.001) |
| 16 | 4.78 ± 2.54 |
5.66 ± 3.47 (0.006) |
5.77 ± 3.47 (0.003) |
1.58 ± 0.79 |
0.99 ± 0.53 (<0.001) |
1.10 ± 0.57 (<0.001) |
| 18 | 4.33 ± 1.99 |
5.06 ± 3.08 (<0.001) |
4.91 ± 2.77 (0.003) |
1.61 ± 0.68 |
1.10 ± 0.54 (<0.001) |
1.11 ± 0.53 (<0.001) |
| 19 | 3.26 ± 1.55 |
3.33 ± 2.58 (<0.001) |
3.48 ± 2.47 (0.004) |
1.21 ± 0.55 |
0.73 ± 0.50 (<0.001) |
0.78 ± 0.49 (<0.001) |
| 22 | 3.91 ± 2.04 |
3.60 ± 2.42 (<0.001) |
4.06 ± 2.69 (0.128) |
1.43 ± 0.69 |
0.80 ± 0.49 (<0.001) |
0.89 ± 0.50 (<0.001) |
The CT volume was normalized for nuclear size by dividing by the nuclear volume. Note that values in parentheses represented KS p‐values when compared to control lymphocytes.