Table 5.
Mean Mander colocalization coefficient (MCC) and percentage of intermingling CTs of lymphocyte and myeloma nuclei studied by 3D‐SIM
| Mean Mander colocalization Coefficient (MCC) | Intermingling volume | |||||
|---|---|---|---|---|---|---|
| Chromosome | Lymphocyte | MGUS | MM | Lymphocyte | MGUS | MM |
| 4 and 14 | 0.12 ± 0.07 |
0.12 ± 0.05 (<0.001) |
0.11 ± 0.06 (0.001) |
6.28 ± 3.87 |
5.68 ± 2.45 (<0.001) |
5.17 ± 2.78 (<0.001) |
| 9 and 22 | 0.12 ± 0.07 |
0.12 ± 0.06 (0.002) |
0.11 ± 0.06 (0.12) |
5.81 ± 3.64 |
5.61 ± 2.69 (<0.001) |
5.14 ± 3.22 (0.09) |
| 11 and 14 | 0.10 ± 0.07 |
0.09 ± 0.04 (0.06) |
0.10 ± 0.06 (0.07) |
5.05 ± 3.61 |
4.32 ± 2.20 (0.06) |
4.71 ± 2.90 (0.09) |
| 14 and 16 | 0.11 ± 0.09 |
0.11 ± 0.06 (0.73) |
0.09 ± 0.06 (0.02) |
5.42 ± 4.55 |
4.97 ± 2.75 (0.69) |
3.99 ± 3.28 (0.02) |
| 18 and 19 | 0.05 ± 0.06 |
0.08 ± 0.06 (<0.001) |
0.07 ± 0.07 (<0.001) |
2.21 ± 2.94 |
3.73 ± 2.78 (<0.001) |
3.23 ± 3.41 (<0.001) |