Table 7.
Shifts From Baseline in Myelosuppression Laboratory Abnormalities
| Baseline severity | n | Maximum on‐treatment severity | ||||
|---|---|---|---|---|---|---|
| Normal | Grade 1 | Grade 2 | Grade 3 | Grade 4 | ||
| Anemia (n) | ||||||
| Normal | 31 | 5 | 12 | 10 | 4 | 0 |
| Grade 1 | 60 | 0 | 21 | 24 | 12 | 3 |
| Grade 2 | 61 | 0 | 4 | 27 | 22 | 6 |
| Grade 3 | 12 | 0 | 1 | 1 | 4 | 6 |
| Grade 4 | 3 | 0 | 0 | 0 | 0 | 3 |
| Total | 167 | 5 | 38 | 62 | 42 | 18 |
| Neutropeniaa (n) | ||||||
| Normal | 83 | 43 | 16 | 10 | 10 | 4 |
| Grade 1 | 44 | 4 | 10 | 4 | 10 | 14 |
| Grade 2 | 17 | 2 | 3 | 1 | 3 | 6 |
| Grade 3 | 9 | 0 | 0 | 3 | 1 | 5 |
| Grade 4 | 13 | 0 | 0 | 0 | 3 | 10 |
| Total | 167 | 49 | 29 | 18 | 27 | 40 |
| Thrombocytopenia (n) | ||||||
| Normal | 72 | 28 | 17 | 6 | 12 | 8 |
| Grade 1 | 29 | 3 | 8 | 1 | 8 | 8 |
| Grade 2 | 10 | 0 | 0 | 0 | 6 | 4 |
| Grade 3 | 25 | 0 | 3 | 0 | 4 | 18 |
| Grade 4 | 31 | 0 | 0 | 0 | 1 | 30 |
| Total | 167 | 31 | 28 | 7 | 31 | 68 |
Severity based on National Cancer Institute Common Terminology Criteria for Adverse Events, version 3.0.
One patient had missing baseline absolute neutrophil count data.