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. 2016 Dec 1;11(12):e0167599. doi: 10.1371/journal.pone.0167599

Fig 5. Inhibition of BCL2 and MCL1: effect on proliferation.

Fig 5

The effect of A) A-1210477 (MCL1 inhibitor) and B) ABT-263 (BCL2 inhibitor) on proliferation of DLBCL cell lines was assessed by 3H-thymidine uptake (d2). Cell lines OCI-LY1 and RI-1 are MCL1neg/BCL2pos, cell line U-2932 is MCL1pos/BCL2pos and cell line U-2946 is MCL1pos/BCL2neg. Especially note the significant reduction of 3H-thymidine incorporation in cell line U-2946 after addition of the MCL1 inhibitor.