Table 3. Univariate and multivariate Cox regression models of all-cause mortality, CVD mortality and infection mortality for RDW groups (RDW>14.9% versus RDW ≤ 14.9%).
All-cause mortality | CVD mortality | infection mortality | ||||
---|---|---|---|---|---|---|
Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
Univariate model | 2.42(1.77,3.31) | <0.001 | 2.45(1.26,4.76) | 0.008 | 2.54(1.61,4.00) | <0.001 |
Model 1 | 2.29(1.67,3.13) | <0.001 | 2.25(1.16,4.37) | 0.017 | 2.39(1.51,3.77) | <0.001 |
Model 2 | 2.09(1.50,2.90) | <0.001 | 2.25(1.16,4.37) | 0.017 | 2.39(1.51,3.77) | <0.001 |
Model 3 | 2.18(1.56,3.03) | <0.001 | 2.27(1.15,4.41) | 0.016 | 1.90(1.15,3.14) | 0.012 |
Model 4 | 2.19(1.55,3.09) | <0.001 | 2.28(1.14,4.52) | 0.019 | 1.90(1.15,3.14) | 0.012 |
Univariate model: unadjusted HR for RDW.
Model 1: RDW, age, sex, BMI and smoking status.
Model 2: Model 1 plus proteinuria, albumin, BUN, calcium, cholesterol, creatinine, eGFR, hemoglobin, MCV, phosphate, platelet count, triglyceride, uric Acid, WBC count, Ca x P.
Model 3: Model 2 plus ACE inhibitor/ IARB, vitamin B12, iron preparation, folic acid supplement, calcium channel blocker, erythropoiesis stimulating agents, phosphate binder
Model 4: Model 3 plus cancer, cerebrovascular disease, chronic lung disease, congestive heart failure, coronary artery disease, dementia, DM, hypertension, hyperlipidemia, liver cirrhosis, and peripheral arterial disease