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. 2016 Dec 1;11(12):e0162025. doi: 10.1371/journal.pone.0162025

Table 3. Univariate and multivariate Cox regression models of all-cause mortality, CVD mortality and infection mortality for RDW groups (RDW>14.9% versus RDW ≤ 14.9%).

All-cause mortality CVD mortality infection mortality
Hazard ratio (95% CI) p-value Hazard ratio (95% CI) p-value Hazard ratio (95% CI) p-value
Univariate model 2.42(1.77,3.31) <0.001 2.45(1.26,4.76) 0.008 2.54(1.61,4.00) <0.001
Model 1 2.29(1.67,3.13) <0.001 2.25(1.16,4.37) 0.017 2.39(1.51,3.77) <0.001
Model 2 2.09(1.50,2.90) <0.001 2.25(1.16,4.37) 0.017 2.39(1.51,3.77) <0.001
Model 3 2.18(1.56,3.03) <0.001 2.27(1.15,4.41) 0.016 1.90(1.15,3.14) 0.012
Model 4 2.19(1.55,3.09) <0.001 2.28(1.14,4.52) 0.019 1.90(1.15,3.14) 0.012

Univariate model: unadjusted HR for RDW.

Model 1: RDW, age, sex, BMI and smoking status.

Model 2: Model 1 plus proteinuria, albumin, BUN, calcium, cholesterol, creatinine, eGFR, hemoglobin, MCV, phosphate, platelet count, triglyceride, uric Acid, WBC count, Ca x P.

Model 3: Model 2 plus ACE inhibitor/ IARB, vitamin B12, iron preparation, folic acid supplement, calcium channel blocker, erythropoiesis stimulating agents, phosphate binder

Model 4: Model 3 plus cancer, cerebrovascular disease, chronic lung disease, congestive heart failure, coronary artery disease, dementia, DM, hypertension, hyperlipidemia, liver cirrhosis, and peripheral arterial disease