Fig 5. Partial least squares loading plot for phosphatidylethanolamine species.

Wild-type mice were fed regular chow (n = 10) or a saturated fat enriched diet (n = 9) for six months. Plasma, hippocampus and cortex lipid species were quantitated with LC-ESI-MS/MS. Partial least squares regression was used to identify plasma lipid species that account for the major sources of variation within the (A) hippocampus and (B) cortex. Using the first latent variable for phosphatidylethanolamine species, loadings for plasma lipids are distributed on the X-axis, while loadings for hippocampus/cortex lipids are on the Y-axis. The X-axis is a measure of correlation to explaining the variation in the brain region. The Y-axis is a measure of correlation to the major source of variation in the brain region. Loadings are from the jack-knife resampled global model.