Table 1.

Expression of Cdk5 in human cancers

Cancer	Cdk5 function	References
Breast	Proliferation, survival, EMT, metastasis	[15, 16]
Colorectal	Proliferation	[78]
Gastric	Cell cycle suppressor	[20]
Glioma, glioblastoma	Invasion	[17, 18]
Hepatocellular carcinoma	Migration, angiogenesis, inflammation, lymphatic development	[21, 34]
Head and Neck -	Not known	[19]
Leukemia	Survival	[79]
Lung - Small cell lung cancer (SCLC), carcinoids	Proliferation, migration	[42]
Lung – Non small cell lung cancer (NSCLC)	Proliferation, migration, invasion	[4, 14]
Mantle cell lymphoma	Proliferation	[80]
Medulloblastoma	Immune evasion	[62]
Melanoma	Proliferation, invasion	[45]
Multiple myeloma	Not known	[81]
Ovary	Migration	[19]
Pancreatic	Proliferation, migration, invasion, metastasis	[6, 44]
Pituitary Adenoma	Migration, invasion	[13]
Prostate	Proliferation, migration, invasion, metastasis, apoptosis	[43]
Thyroid - Medullary thyroid carcinoma	Proliferation	[12]