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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Trends Cancer. 2016 Oct;2(10):606–618. doi: 10.1016/j.trecan.2016.09.001

Table 1.

Expression of Cdk5 in human cancers

Cancer Cdk5 function References
Breast Proliferation, survival, EMT, metastasis [15, 16]
Colorectal Proliferation [78]
Gastric Cell cycle suppressor [20]
Glioma, glioblastoma Invasion [17, 18]
Hepatocellular carcinoma Migration, angiogenesis, inflammation, lymphatic development [21, 34]
Head and Neck - Not known [19]
Leukemia Survival [79]
Lung - Small cell lung cancer (SCLC), carcinoids Proliferation, migration [42]
Lung – Non small cell lung cancer (NSCLC) Proliferation, migration, invasion [4, 14]
Mantle cell lymphoma Proliferation [80]
Medulloblastoma Immune evasion [62]
Melanoma Proliferation, invasion [45]
Multiple myeloma Not known [81]
Ovary Migration [19]
Pancreatic Proliferation, migration, invasion, metastasis [6, 44]
Pituitary Adenoma Migration, invasion [13]
Prostate Proliferation, migration, invasion, metastasis, apoptosis [43]
Thyroid - Medullary thyroid carcinoma Proliferation [12]