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. 2016 Winter;15(4):ar65. doi: 10.1187/cbe.15-12-0267

TABLE 3.

Examples of student responses and rubric coding, with each response shown given by a different student.

Bins
Question 1: Correct 2: Incomplete/irrelevant 3: Incorrect
Replication It will not have any effect on the replication process. This would be an example of a nonsense mutation. The DNA will stop replicating when it reaches the stop codon.
Transcription It will not have any effect on transcription. This will cause a mutation in the transcription process. In the process of transcribing DNA into RNA, the newly added stop codon will inhibit the rest of the chain from being transcribed into RNA.
Translation This will influence translation because the stop codon will cause the amino acid sequence to end before it should. This will create a different polypeptide or protein that will either not function or function differently than it should have. The code will be translated with a different base and will be read differently. This will result in a different protein being built. This will have no influence on translation.