Table 1. iTRAQ-based quantification compared with MRM-based quantification.
| Gene symbol | Uniprot accession | Protein name | Unique peptides(iTRAQ) | iTRAQ ratios DP3/DP9(Mean) | MRM ratios DP3/DP9 | Expression pattern |
|---|---|---|---|---|---|---|
| PLOD2 | sp|O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | 7 | 0.499 | 0.438 | down |
| DCN | sp|P07585 | Decorin | 8 | 4.603 | 12.555 | up |
| THBS1 | sp|P07996 | Thrombospondin-1 | 1 | 0.272 | 0.579 | down |
| MMP3 | sp|P08254 | Stromelysin-1 | 1 | 3.11 | 4.313 | up |
| COL4A2 | sp|P08572 | Collagen alpha-2(IV) chain | 16 | 0.592 | 0.285 | down |
| ACTN1 | sp|P12814 | Alpha-actinin-1 | 22 | 0.564 | 0.475 | down |
| IGFBP4 | sp|P22692 | Insulin-like growth factor-binding protein 4 | 4 | 1.601 | 1.755 | up |
| FBLN1 | sp|P23142 | Fibulin-1 | 5 | 1.977 | 10.989 | up |
| IGFBP5 | sp|P24593 | Insulin-like growth factor-binding protein 5 | 4 | 0.381 | 0.21 | down |
| SERPINF1 | sp|P36955 | Pigment epithelium-derived factor | 10 | 5.711 | 80.361 | up |
| CXCL12 | sp|P48061 | Stromal cell-derived factor 1 | 2 | 4.7 | 13.229 | up |
| ACLY | sp|P53396 | ATP-citrate synthase | 6 | 0.497 | 0.581 | down |
| FMOD | sp|Q06828 | Fibromodulin | 2 | 4.982 | 8.867 | up |
| FLNC | sp|Q14315 | Filamin-C | 26 | 0.488 | 0.295 | down |
| LTBP1 | sp|Q14766 | Latent-transforming growth factor beta-binding protein 1 | 8 | 3.039 | 5.93 | up |
| AEBP1 | sp|Q8IUX7 | Adipocyte enhancer-binding protein 1 | 12 | 3.201 | 8.103 | up |
| SPON2 | sp|Q9BUD6 | Spondin-2 | 7 | 1.269 | 1.649 | up |
| PDGFD | sp|Q9GZP0 | Platelet-derived growth factor D | 3 | 2.267 | 2.516 | up |
| DPP7 | sp|Q9UHL4 | Dipeptidyl peptidase 2 | 6 | 1.876 | 2.338 | up |