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. 2016 Dec 1;11(12):e0165997. doi: 10.1371/journal.pone.0165997

Table 2. Most Tweeted Papers in the Nature.

Rank Title Discipline Keywords Date Tweets
1 Artificial sweeteners induce glucose intolerance by altering the gut microbiota Biology sciences Type 2 diabetes mellitus, Microbiome, Metabolic syndrome, Metagenomics 2014/9/17 3664
2 Stimulus-triggered fate conversion of somatic cells into pluripotency Biology sciences Reprogramming 2014/1/29 3442
3 A new antibiotic kills pathogens without detectable resistance Biology sciences Natural products, Target identification, Antibiotics, Antimicrobial resistance 2015/1/7 2466
4 Selective corticostriatal plasticity during acquisition of an auditory discrimination task Biology sciences Neuroscience 2015/3/2 1995
5 Observation of Dirac monopoles in a synthetic magnetic field Physical sciences Ultracold gases, Bose-Einstein condensates, Quantum fluids and solids 2014/1/29 1720
6 The geographical distribution of fossil fuels unused when limiting global warming to 2°C Earth & environment sciences Climate-change mitigation 2015/1/7 1387
7 Structural and functional features of central nervous system lymphatic vessels Biology sciences Neuroimmunology, Lymphatic vessels 2015/6/1 1169
8 Bidirectional developmental potential in reprogrammed cells with acquired pluripotency Biology sciences Stem cells 2014/1/29 1122
9 Human-level control through deep reinforcement learning Physical sciences Computer science 2015/2/25 962
10 No increase in global temperature variability despite changing regional patterns Earth & environment sciences Climate and Earth system modelling 2013/7/24 806
11 A semi-synthetic organism with an expanded genetic alphabet Biology sciences Synthetic biology, DNA metabolism, DNA replication 2014/5/7 768
12 3.3-million-year-old stone tools from Lomekwi 3, West Turkana, Kenya Biology sciences Archaeology 2015/5/20 761
13 Cerebral organoids model human brain development and microcephaly Biology sciences Biological models, Neurogenesis, Stem cells, Diseases of the nervous system 2013/8/28 738
14 Complex archaea that bridge the gap between prokaryotes and eukaryotes Biology sciences Archaeal evolution, Origin of life, Metagenomics 2015/5/6 709
15 Attractive photons in a quantum nonlinear medium Physical sciences Atomic and molecular interactions with photons, Nonlinear optics, Quantum optics, Quantum mechanics 2013/9/25 695