Table 2.
Crude and adjusteda odds ratios (95% CIs) for the association between fungal and bacterial diversity (Simpson index, tertiles) and health outcomes.
| Model | Crude analyses | Adjusteda analyses | ||
|---|---|---|---|---|
| Fungal diversity | Bacterial diversity | Fungal diversity | Bacterial diversity | |
| Logisitic regression models | ||||
| Sensitization to aero-allergens (6 years) | n = 157 | n = 157 | ||
| 2nd tertile vs. 1st tertile | 0.79 (0.35, 1.80) | 0.63 (0.27, 1.47) | 0.66 (0.28, 1.56) | 0.56 (0.23, 1.33) |
| 3rd tertile vs. 1st tertile | 0.31 (0.12, 0.79) | 0.53 (0.22, 1.24) | 0.26 (0.10, 0.70) | 0.45 (0.18, 1.11) |
| Sensitization to aero-allergens (10 years) | n = 140 | n = 140 | ||
| 2nd tertile vs. 1st tertile | 1.41 (0.61, 3.22) | 0.71 (0.31, 1.58) | 1.13 (0.47, 2.70) | 0.59 (0.25, 1.38) |
| 3rd tertile vs. 1st tertile | 1.32 (0.57, 3.07) | 0.63 (0.27, 1.45) | 1.01 (0.41, 2.51) | 0.45 (0.18, 1.11) |
| Wheezing ever (10 years) | n = 168 | n = 168 | ||
| 2nd tertile vs. 1st tertile | 0.61 (0.29, 1.28) | 0.62 (0.29, 1.33) | 0.59 (0.27, 1.28) | 0.60 (0.28, 1.30) |
| 3rd tertile vs. 1st tertile | 0.45 (0.21, 0.95) | 1.00 (0.48, 2.07) | 0.42 (0.18, 0.96) | 1.00 (0.45, 2.06) |
| GEE models (longitudinal analysis) | ||||
| Sensitization to aero-allergens until 10 years | n = 110 | n = 110 | ||
| 2nd tertile vs. 1st tertile | 1.04 (0.51, 2.12) | 0.58 (0.29, 1.19) | 0.89 (0.34, 2.32) | 0.79 (0.33, 1.90) |
| 3rd tertile vs. 1st tertile | 0.69 (0.33, 1.41) | 0.51 (0.25, 1.04) | 0.61 (0.24, 1.59) | 0.56 (0.22, 1.42) |
| Wheezing until 10 years | n = 159 | n = 159 | ||
| 2nd tertile vs. 1st tertile | 0.83 (0.45, 1.54) | 0.81 (0.41, 1.57) | 0.78 (0.40, 1.51) | 0.74 (0.36, 1.53) |
| 3rd tertile vs. 1st tertile | 0.50 (0.26, 0.98) | 1.14 (0.62, 2.09) | 0.57 (0.26, 1.22) | 0.98 (0.52, 1.84) |
| aAdjusted for sex, maternal education, and season of dust sampling. | ||||