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. 2016 Jun 3;124(12):1876–1881. doi: 10.1289/EHP176

Table 2.

Association of plasma manganese concentrations with T2D.

Variables Tertiles of plasma manganese concentrations (μg/L)
1 (Lowest) ≤ 4.21 μg/L 2 4.21–6.84 3 (Highest) ≥ 6.84 μg/L
n(NGT/T2D) 538/780 541/377 535/457
Crude 2.08 (1.75, 2.47) 1 1.23 (1.02, 1.47)
Model 1 2.08 (1.73, 2.49) 1 1.28 (1.05, 1.55)
Model 2 2.15 (1.75, 2.63) 1 1.54 (1.23, 1.92)
Model 3 1.89 (1.53, 2.33) 1 1.56 (1.23, 1.97)
Model 1, adjusted for age, sex, and body mass index. Model 2, adjusted for Model 1, current smoking status, current alcohol drinking status, physical activity, family history of diabetes, and hypertension. Model 3, adjusted for Model 2, plasma iron, plasma copper, and plasma selenium.