Table 3.
Adjusted ORs for plasma manganese levels associated with T2D in subgroups.
| Groups | Tertiles of plasma manganese concentration (μg/L) | p-Value for interaction | ||
|---|---|---|---|---|
| 1 (Lowest) | 2 | 3 (Highest) | ||
| Sex | ||||
| Male | 2.14 (1.62, 2.83) | 1 | 1.28 (0.96, 1.72) | 0.06 |
| Female | 2.31 (1.69, 3.17) | 1 | 2.06 (1.47, 2.90) | |
| Age | ||||
| < 55 | 1.81 (1.34, 2.45) | 1 | 1.30 (0.94, 1.79) | < 0.01 |
| ≥ 55 | 2.45 (1.80, 3.33) | 1 | 1.77 (1.28, 2.45) | |
| BMI | ||||
| < 24 | 2.17 (1.62, 2.90) | 1 | 1.47 (1.07, 2.01) | 0.45 |
| ≥ 24 | 2.26 (1.70, 3.02) | 1 | 1.67 (1.24, 2.26) | |
| Physical activity | ||||
| No or rare | 1.97 (1.52, 2.56) | 1 | 1.37 (1.02, 1.82) | < 0.01 |
| Yes | 1.55 (1.06, 2.25) | 1 | 2.11 (1.38, 3.22) | |
| Current smoking | ||||
| Yes | 2.21 (1.50, 3.26) | 1 | 1.18 (0.79, 1.75) | 0.21 |
| No | 2.22 (1.74, 2.84) | 1 | 1.76 (1.36, 2.29) | |
| Current drinking | ||||
| Yes | 1.84 (1.22, 2.78) | 1 | 1.27 (0.84, 1.93) | 0.49 |
| No | 2.36 (1.85, 3.00) | 1 | 1.73 (1.34, 2.24) | |
| Family history of diabetes | ||||
| Yes | 1.95 (1.09, 3.49) | 1 | 1.31 (0.71, 2.43) | 0.73 |
| No | 2.29 (1.84, 2.86) | 1 | 1.62 (1.29, 2.05) | |
| Hypertension | ||||
| Yes | 2.62 (1.81, 3.80) | 1 | 1.42 (0.97, 2.10) | 0.12 |
| No | 2.07 (1.61, 2.66) | 1 | 1.66 (1.27, 2.15) | |
| Adjusted for age, sex, body mass index, current smoking status, current alcohol drinking status, physical activity, family history of diabetes, hypertension, plasma iron, plasma copper, and plasma selenium. | ||||