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. 2016 Apr 29;124(12):1830–1839. doi: 10.1289/EHP212

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TEMPOL treatment prevents concentrated fine particulate matter (CAP)-induced vascular insulin resistance and inflammation. Western blot analysis of (A) the insulin-stimulated phosphorylation of Akt and (B) the abundance of IκBα in aortas of mice treated with water or TEMPOL (1 mM, in drinking water) exposed to air or CAP for 9 days (Study IV). The continuous IκBα Western blot is shown in Figure S4B. Data are the mean ± SE normalized to controls. *p < 0.05 control versus insulin; ^# p < 0.05 air versus CAP. Phospho-Akt, n = 5–10; IκBα, n = 4–5.