Table 3.
Risk for elevated C-reactive protein concentration (≥1 mg/L) at follow-up by body weight status.
| Underweight/Normal Weight §
# Follow up Visits = 3526 |
Overweight and Not Obese §
# Follow up Visits = 4028 |
Obese §
# Follow up Visits = 2829 |
||||
|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| Serum 25(OHD) at baseline, nmol/L | ||||||
| <50 | ref | ref | ref | |||
| 50–<75 | 0.71 (0.42, 1.19) | 0.19 | 0.82 (0.57, 1.20) | 0.31 | 0.59 (0.38, 0.92) | 0.02 |
| 75–<100 | 0.63 (0.38, 1.05) | 0.08 | 0.58 (0.39, 0.86) | 0.01 | 0.66 (0.40, 1.10) | 0.11 |
| 100–<125 | 0.67 (0.39, 1.16) | 0.15 | 0.62 (0.39, 0.96) | 0.03 | 0.51 (0.27, 0.96) | 0.04 |
| ≥125 | 0.64 (0.36, 1.14) | 0.13 | 0.69 (0.43, 1.13) | 0.14 | 0.35 (0.17, 0.73) | <0.01 |
| Change in serum 25(OH)D, nmol/L | ||||||
| No improvement | ref | ref | ref | |||
| Increase of <25 | 1.16 (0.79, 1.68) | 0.45 | 0.90 (0.64, 1.27) | 0.55 | 0.62 (0.39, 1.00) | 0.05 |
| Increase of 25–<50 | 1.12 (0.76, 1.67) | 0.56 | 0.79 (0.55, 1.12) | 0.18 | 0.58 (0.35, 0.96) | 0.03 |
| Increase of 50–<75 | 1.25 (0.82, 1.91) | 0.30 | 0.86 (0.58, 1.26) | 0.43 | 0.54 (0.32, 0.92) | 0.02 |
| Increase of ≥75 | 1.40 (0.92, 2.13) | 0.12 | 0.82 (0.56, 1.20) | 0.30 | 0.52 (0.31, 0.89) | 0.02 |
Abbreviations: OR, Odds Ratio; 95% CI, 95% Confidence Interval; CVD, cardiovascular disease; CRP, C-reactive protein; LDL-cholesterol, low density lipoprotein cholesterol; § Adjusted for elevated CRP at baseline, LDL-cholesterol at baseline, age at baseline, gender, blood pressure status baseline, smoking status at baseline, alcohol consumption status at baseline, and physical activity level at baseline, and change in physical activity level in addition to variables in the table.