Table 7.
Effect of pterocarpan-high soy leaf extract supplementation on changes of plasma PAI-1, adipokine and cytokine levels in subjects with metabolic syndrome.
| Placebo | PT | Time × Group, p Value † | |||
|---|---|---|---|---|---|
| Before | After | Before | After | ||
| PAI-1 (ng/mL) | 9.22 ± 0.47 | 10.28 ± 1.18 | 11.95 ± 1.01 | 10.18 ± 1.11 * | 0.044 |
| TNF-α (pg/mL) | 12.86 ± 0.92 | 12.92 ± 0.72 | 12.71 ± 0.60 | 11.52 ± 0.51 * | 0.031 |
| IL-6 (pg/mL) | 6.14 ± 0.13 | 5.80 ± 0.11 | 6.51 ± 0.38 | 5.96 ± 0.21 * | 0.872 |
| MCP-1 (pg/mL) | 124.47 ± 13.66 | 131.52 ± 11.20 | 141.13 ± 10.00 | 126.72 ± 9.41 | 0.370 |
| Adiponectin (ng/mL) | 73.10 ± 10.55 | 65.92 ± 7.58 | 75.63 ± 8.29 | 71.06 ± 8.47 | 0.803 |
| Leptin (pg/mL) | 13.39 ± 1.66 | 14.16 ± 1.69 | 13.79 ± 1.55 | 13.40 ± 1.39 | 0.312 |
Values are the mean ± SE. Placebo, starch; PT, pterocarpan-high soy leaf extract (2 g/day); PAI-1, plasminogen activator inhibitor-1; TNF-α, tumor necrosis factor-α; MCP1, monocyte chemotactic protein 1; IL-6: interleukin-6. * p < 0.05 paired t-test between before and after trial in each group. † p < 0.05 general linear model for repeated measures ANOVA.