Figure 8.

Blocking of dectin-1 affects human PBMC cytokine induction in response to C. guilliermondii. Human PBMCs were pre-incubated with laminarin for 1 h at 37°C prior to co-culture with yeast cells. After 24 h incubation at 37°C, the supernatants were saved and used to quantify cytokine levels. Results (means ± SD) were obtained using samples from six donors, each assayed in duplicate wells. The strains used are: KU141 (Parental) and HMY134 (pmr1Δ). ^*P < 0.05, when compared to the same yeast cell type without treatment.