Table 1. Clinical and pathological characteristics of the study cohort.
| Variables | Study cohort |
|---|---|
| No. of patients | 2342 |
| Practice type | |
| Academic | 249 (10.6%) |
| Community | 2092 (89.3%) |
| Unknown | 1 (0%) |
| Age at RP | |
| Median (range) | 66 (40–84) |
| IQR (Q1, Q3) | (60–69) |
| Time between RP and ordering of Decipher (months) | |
| Median (range) | 3.6 (0.1–102) |
| IQR (Q1, Q3) | (0.8–14.8) |
| Pre-op PSA (ng−1ml) | |
| Median (range) | 6.4 (0–150) |
| IQR (Q1, Q3) | (4.7–9.6) |
| <10 ng ml−1 | 1265 (54.0%) |
| 10-20 ng ml−1 | 277 (11.8%) |
| >20 ng ml−1 | 110 (4.7%) |
| Unknown | 690 (29.5%) |
| Extra-prostatic extension, n (%) | |
| Present | 1297 (55.4%) |
| Seminal vesicle invasion,a n (%) | |
| Present | 504 (21.5%) |
| Surgical margin,a n (%) | |
| Positive | 1271 (54.3%) |
| Lymph node invasion,a n (%) | |
| Positive | 61 (2.6%) |
| Pathologic Gleason score, n (%) | |
| 6 | 186 (7.9%) |
| 7 | |
| (3+4) | 900 (38.4%) |
| (4+3) | 674 (28.8%) |
| 8 | 251 (10.7%) |
| 9–10 | 328 (14.0%) |
| Unknown | 3 (0.1%) |
| Pathological stage, n (%) | |
| T2R0 | 349 (14.9%) |
| T2R1 | 564 (24.1%) |
| T3a | 903 (38.6%) |
| T3b | 501 (21.4%) |
| T4 | 14 (0.6%) |
| Unknown | 11 (0.5%) |
Abbreviations: IQR, interquartile range; RP, radical prostatectomy.
a
Unknown seminal vesicle invasion, surgical margin and lymph node invasion status for 11, 6 and 95 patients, respectively.