Figure 1.

Switches between anticoagulation drugs. Each line represents 1 patient. Three patients switched from dabigatran to VKA (1 – mechanical valve, 1 – financial reasons, 1 – unknown reasons), 3 switched from VKA to rivaroxaban (2 – labile INR, 1 – enrolled in a rivaroxaban drug trial), 2 switched from dabigatran to rivaroxaban (1 – allergic reaction to dabigatran, 1 – unknown reasons), 2 switched from rivaroxaban to VKA (1 – bleeding complications, 1 – unknown reasons) and 1 switched from VKA to dabigatran (unknown reasons)

LMWH – low molecular weight heparin, VKA – vitamin K antagonists.