c-FOS expression in the granule cell layer of the OB and AOB in WT vs Bmal1 KO males after exposure to estrous female scent. A, WT control OB. B, WT + estrous female scent OB. C, Bmal1 KO control OB. D, Bmal1 KO + estrous female scent OB. E, Dotted outline indicates quantified portion. Images were obtained from the Allen Mouse Brain Atlas (http://mouse.brain-map.org). F, Quantification of c-FOS-positive cells in defined area. G, WT control AOB. H, WT + estrous female scent AOB. I, Bmal1 KO control AOB. J, Bmal1 KO + estrous female scent AOB. K, Dotted outline indicates quantified portion. Images obtained from the Allen Institute web site. L, Quantification of c-FOS-positive cells in defined area (n = 3 animals per treatment group). *, P < .5, **, P < .01, ***, P < .001, by ANOVA followed by Tukey post hoc. Scale bar, 100 μm. Image reproduced with permission from the Allen Institute.